Master’s Thesis: Antibacterial effects of ultrathin ceramic surfaces
[APPLICATION CLOSED]
Bacteria living on surfaces are called biofilms and they cause up to 80% of all infections. They are difficult to eradicate using antibiotics and can be the reason for implant removal. Thus they are important to study in relation to implants.
Aim
The aim of this master project is to develop an in vitro method to study potential antibacterial effects of ultrathin ceramic surfaces that are used on dental and orthopedic implants.
In this project early and mature, (2 or 24 h), biofilms will be cultured on different ultrathin ceramic surfaces in vitro and be compared to growth on titanium surfaces. Different methods to remove bacteria from the surfaces will be tested, including detergents and sonication. The biofilm bacteria will be investigated with culturing on agar plates and different metabolic stains using spectrophotometric methods. Potentially bacterial growth may also be studied using scanning electron microscopy.
We are looking for a candidate…
- With a background in Biotechnology and/or Microbiology
- Who learns fast, can work independently, is motivated and a team-player
- With fluency in English
- Who is proficient in Microsoft Word and Excel
- With previous lab work experience (including experience from University)
Who are we?
Promimic’s nanotechnology, HAnano Surface, creates a unique bioactive surface on any implant. The HAnano Surface has demonstrated faster and stronger osseointegration in over 30 clinical studies, with over 1.4 million clinical applications to date.
The HAnano Surface is a 20 nanometer thin implant surface treatment composed of crystalline hydroxyapatite (HA) particles, which have the same shape, composition, and structure as HA found in human bone.
We are located in GoCo Health Innovation City in Mölndal, easily accessible by car, bike or bus from Gothenburg.
What can we offer?
Promimic offers a hands-on research opportunity in the field of nano-surface technologies and material surfaces. As part of our team, students can contribute to cutting-edge projects that focus on enhancing the performance of medical implants. This involves applying theoretical knowledge to develop innovative solutions, with access to specialized labs, equipment, and resources not typically found in academic settings. It’s a chance to contribute meaningfully to healthcare advancements while gaining practical experience in a real-world application. Compensation is included.
Start: January 2024Duration: 20 weeks